A New Light for Chronic Conditions: The Supportive Promise of Expanded Mesenchymal Stem Cells
Expanded Mesenchymal Stem Cells (MSCs) safely support chronic conditions, easing symptoms, slowing progression, and improving quality of life.
When a cure isn’t possible, Care and Support still change lives.
Even when a definitive cure is not possible, Expanded Mesenchymal Stem cells (MSCs) offer a scientifically validated, safe, and side-effect–free supportive treatment in a wide range of chronic, degenerative, or treatment-resistant diseases. Their anti-inflammatory, immunomodulatory, anti-fibrotic, and regenerative properties contribute to improving quality of life, stabilizing symptoms, and slowing disease progression.
Scientifically Supported, Side-Effect-Free supportive uses include:
Chronic Obstructive Pulmonary Disease (COPD)
MSCs help reduce lung inflammation, improve pulmonary function, and stabilize respiratory symptoms.Multiple Sclerosis (MS)
While not curative, MSCs may slow neuroinflammation and enhance neurological recovery.Liver Cirrhosis & Chronic Liver Disease
MSCs reduce fibrosis and improve liver function without adverse effects.Crohn’s Disease & Ulcerative Colitis (IBD)
Their immunomodulatory effects help control relapses and reduce the need for immunosuppressive drugs.Idiopathic Pulmonary Fibrosis (IPF)
MSCs may slow fibrotic progression and improve oxygenation and exercise tolerance.Systemic Lupus Erythematosus (SLE)
MSCs help modulate immune dysfunction and reduce systemic flares.Spinal Cord Injury (Chronic Phase)
They support neuroprotection and reduce secondary inflammation, promoting limited functional recovery.Type 1 Diabetes (Early-Stage or Recent-Onset)
MSCs protect pancreatic β-cells and delay autoimmune destruction, although they do not reverse established diabetes.Heart Failure (Ischemic and Non-Ischemic Cardiomyopathy)
MSCs can improve cardiac function and reduce inflammatory remodeling of heart tissue.
Even in cases where chronic or degenerative conditions are not curable, expanded Mesenchymal Stem Cells (MSCs) can offer powerful supportive benefits—without the side effects of conventional treatments. Thanks to their anti-inflammatory, anti-fibrotic, immunomodulatory, and regenerative actions, MSCs can improve quality of life, reduce symptom severity, and slow the progression of disease. Most importantly, their excellent safety profile has been validated in multiple clinical trials.
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Supporting Studies Key References
Condition
What MSCs Can Do
Supportive Benefits
Supporting Studies
Key References
COPD
Improve lung function and reduce inflammation
Weiss et al., Chest, 2013 [PMID: 23681064]
Multiple Sclerosis
Modulate immune response, reduce relapse rate
Llufriu et al., J Transl Med, 2014 [PMID: 24885658]
Liver Cirrhosis
Improve liver function, reduce fibrotic damage
Lin et al., Stem Cell Res Ther, 2011 [PMID: 21232138]
Crohn’s Disease
Heal fistulas, reduce dependency on drugs
Panés et al., Lancet, 2016 [PMID: 26947890]
Pulmonary Fibrosis
Slow fibrotic progression, support oxygenation
Tzouvelekis et al., Chest, 2013 [PMID: 23732584]
Systemic Lupus (SLE)
Reduce flares and systemic inflammation
Wang et al., Arthritis Res Ther, 2014 [PMID: 25243800]
Spinal Cord Injury
Support limited motor recovery, reduce scarring
Vaquero et al., Cytotherapy, 2016 [PMID: 26921693]
Type 1 Diabetes (early stage)
Protect insulin-producing cells
Carlsson et al., Diabetes Care, 2015 [PMID: 26216877]
Heart Failure
Improve cardiac output and tissue repair
Bartolucci et al., JACC, 2017 [PMID: 28545673]
Why choose MSCs for Supportive Care?
Backed by dozens of human trials with excellent safety profiles
Allogeneic use approved in many studies, Safe for both autologous and allogeneic use - no HLA matching or immunosuppressants needed
No teratoma formation and no systemic side effects - Non-immunogenic and non-tumorigenic
Complementary to standard therapies (e.g., immunosuppressants, DMARDs, steroids), Can be used alongside conventional therapie
No long-term adverse effects
The Stem Cell Source
Mesenchymal stem cells are the same regardless of whether they are derived from Adipose Tissue or Umbilical Cord Tissue. The only difference lies in their biological age, which reflects the age of the tissue of origin.
Adipose Tissue Derived Stem Cells
Umbilical Cord Tissue derived Stem Cells
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Expanded Mesenchymal Stem Cells are Supportive - and Stromal Vascular Fraction can be harmful
Expanded MESENCHYMAL STEM CELLS (MSCS) offer a highly purified, potent, and safe form of regenerative support in a wide range of chronic and inflammatory conditions. By contrast, STROMAL VASCULAR FRACTION (SVF) - a heterogeneous, minimally processed mixture extracted from adipose tissue - may actually worsen certain conditions due to its uncontrolled cellular composition. When it comes to regenerative medicine, not all cell
therapies are the same. Many clinics offer stromal vascular fraction (SVF) as a quick solution—but what they don’t tell you is that SVF contains a large number of inflammatory cells that may actually worsen your condition.
In contrast, expanded Mesenchymal Stem Cells (MSCs) provide a targeted, purified, and scientifically validated supportive therapy with anti-inflammatory and regenerative effects.
MSCs offer Supportive Benefits
Purity and Consistency
Expanded MSCs are isolated, cultured, and characterized under strict GMP conditions. This ensures a defined, homogeneous population of anti-inflammatory and immunomodulatory cells.Anti-Inflammatory & Anti-Fibrotic Action
MSCs exert paracrine effects that suppress inflammatory cytokines, modulate immune overactivation, and reduce fibrosis - core drivers in many chronic diseases.No Pro-Inflammatory Cells Present
Unlike SVF, expanded MSCs are depleted of immune cells that could trigger inflammatory cascades. They are typically negative for CD45, CD14, and other hematopoietic markers.
SVF are Harmful in Inflammatory or Degenerative Conditions
High Macrophage Content
SVF contains a large proportion of pro-inflammatory M1 macrophages and other immune cells, such as T cells and neutrophils, which can amplify local or systemic inflammation.Heterogeneous and Unpredictable
SVF is a non-standardized cocktail of cell types - adipose-derived stem cells, endothelial cells, fibroblasts, pericytes, and macrophages - with unknown ratios, making its effects unpredictable and potentially counterproductive.Risk of Exacerbating Disease Mechanisms
In diseases where chronic inflammation, fibrosis, or immune dysregulation are already present (e.g., autoimmune diseases, arthritis, fibrosis, neuroinflammation), SVF may aggravate symptoms rather than alleviate them.
MSCs are Clean, Controlled, and clinically Safe
Purified Cell Population
Expanded MSCs are isolated and expanded in GMP-certified labs to ensure a homogeneous, inflammation-free product.Anti-inflammatory and Regenerative
These cells naturally reduce inflammation, modulate immune responses, and promote tissue repair.No Immune Cells, No Side Effects
Expanded MSCs are free from pro-inflammatory macrophages, T-cells, and other immune components that can trigger adverse reactions.Clinically Tested in Humans
Dozens of peer-reviewed clinical trials confirm the safety and supportive benefits of expanded MSCs in conditions like osteoarthritis, autoimmune diseases, COPD, and more.
SVF are a Risky, Unregulated mixture of Inflammatory Cells
High Macrophage Load
SVF contains a large number of M1-type macrophages—cells that actively promote inflammation and tissue damage.Uncontrolled Composition
SVF is a crude extract from fat tissue, containing a mix of immune cells, fibroblasts, endothelial cells, and stem cells, with no control over what’s injected into your body.Can Worsen Inflammation
In chronic or autoimmune conditions, SVF has been shown to exacerbate the inflammatory process, especially in joints, lungs, or fibrotic tissues.Not Expanded or Standardized
Unlike expanded MSCs, SVF is not cultivated, not tested, and not regulated, increasing the risk of inconsistent outcomes and complications.
THE SCIENCE IS CLEAR: Expanded MSCs are safe, anti-inflammatory, and regenerative. SVF is unfiltered, pro-inflammatory, and potentially harmful.
Let’s clarify with accurate information:
Stem Cells obtained from a fat sample require at least two weeks of processing before they can be used; otherwise, the treatment is ineffective and potentially harmful:
- Fat that is harvested and manipulated for use in the same session is both useless and harmful.
- There are no Stem Cells in the blood, so treatments claiming to use stem cells extracted from blood are not scientifically valid. The Stem Cells used to treat hematological diseases are found in the bone marrow, not in the blood.
- The hematopoietic stem cells found in umbilical cord blood are useful for treating blood disorders, but not for counteracting the aging processes of the human body
Learn how Stem Cells can change your life!
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Stromal Vascular Fraction (SVF) VS Mesenchymal Stem Cells (MSC)
At our Clinic, we prioritize precision and efficacy by exclusively using Mesenchymal Stem Cells (MSCs). These are meticulously isolated and expanded in controlled laboratory settings, ensuring a pure, potent, and standardized cell population. This approach enhances the therapeutic potential and consistency of our treatments.
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As the world’s leading center of Stem Cell and Regenerative Medicine, Bioscience offers unparalleled service and treatments, unique only to it. Bioscience offers the most advanced personalized expanded adipose derived Stem Cell therapies across Europe – including Rome, Milan, and San Marino, and the Middle East, including Dubai.
The team at Bioscience Institute does not believe in using invasive surgeries when they can be partially replaced by cell biology. Therefore, they have designed an alternative method of extracting stem cells from adipose tissue. As a distinctive and versatile offering, adipose tissue provides an effective solution to all of Bioscience regenerative services, ranging from to hair loss treatments, to skin aging, to body reshaping treatments.
Bioscience Institute Vision
The beauty of regenerative medicine therapies and Stem Cell treatments comes from the ability to use your own body to help heal and enhance your well-being through living body tissue. Bioscience Institute’s vision is based on using this most effective and advanced Stem Cell treatments that is based on cell biology and Exosomes to help amplify our natural healing process in the areas it is needed most or take over the function of damaged tissue altogether.
Stem cells verified treatments
With the ability to develop methods to regrow, repair, or replace damaged cells and tissues, using Stem Cell & regenerative medicines provides a natural method of treatment that is less traumatic to the body and more effective than other more invasive treatments and surgeries. The stem cell therapies provided by Bioscience Institute are verified in Europe and the Middle East by scientific evidence of increased safety and efficiency than any other treatment method.
Scientific Research
The Bioscience’s profits are consistently reinvested into developing research. Avoiding a flashy commercial profile allows us to concentrate on using investments to create better treatments and ultimately help clients globally. Due to this commitment, Bioscience Institute has instigated important scientific collaborations with leading universities, pioneering procedures and methods around cell products.
Bioscience Cell Factory and Clinic in Dubai, San Marino, Italy & Switzerland
Bioscience Institute is the first and only GMP-certified Clinic in the Middle East and Europe, offering stem cell treatments with the most advanced personalized autologous cell therapies worldwide.
Offering a unique service and treatment sets it apart from any form of competition and allows it to give clients the care, attention, and treatment they deserve.
- Bioscience Clinics in the Middle East and Europe include a fully equipped facility needed to carry out any treatments offered, whether Stem Cell treatments or banking.
- Bioscience Laboratory is a dedicated Cell Banking Factory used to store and expand Adipose-Derived Cells and Fibroblasts to help ensure that the clients’ needs can always and easily be catered to.