Experiencing Joint pain or Cartilage wear? There are alternatives to surgery.

Our treatment offers a non-invasive, science-backed solution that uses your own Stem Cells to naturally repair joints and cartilage—no prosthetics, no surgery, just real regeneration.

This is more than restoring movement... It’s about reclaiming your life.

Imagine running with your kids, hiking without pain, or simply enjoying everyday moments again. With your own Stem Cells, we help your body heal itself—naturally, safely, and powerfully.

Experiencing Joint Pain or Cartilage Wear caused by conditions such as:

Cartilage Lesions

Cartilage lesions, often an early sign of osteoarthritis, are a common target of our treatment, which helps relieve chronic joint pain and stiffness.

Tendon and muscle injuries

Tendon and muscle injuries often affect active individuals, especially in high-impact sports. They can also be linked to muscle imbalances or endocrine issues like thyroid disorders.

Arthrosis

Arthrosis is a degenerative disease that wears down joint cartilage—and sometimes bone—causing painful friction and limited mobility.

These conditions:

  • Typically result in pain, swelling, and stiffness, all of which can restrict range of motion and limit movement.

  • Are degenerative processes that affect bones, cartilage and tendons

These Degenerative processes...

Can only be treated with Regenerative Medicine because other treatments can only reduce the symptoms of degenerative processes but do not counteract the process itself.

Why Mesenchymal Stem Cell (MSC)?

Regenerative treatments like Mesenchymal Stem Cell Therapy, work at the root cause—not just on the surface - because it addresses the causes of hair loss, not just the symptoms.
MSC- based treatments aim to reverse or slow the aging process at the cellular level by stimulating tissue repair and regeneration.
Our treatment offers a non-invasive, science-backed solution that uses Mesenchymal Stem Cells to naturally repair joints and cartilage — no drug, no prosthetics, no surgery, just tissue regeneration - because MSCs can differentiate into specific cells of joint tissues, such as:

  • Chondrocytes (cartilage cells)

  • Osteoblasts (bone cells)

  • Tenocytes (tendon cells)

This enables the structural regeneration of damaged tissues, such as cartilage, subchondral bone, or tendons. MSCs replace damaged cells and create a microenvironment that promotes regeneration and reduces inflammation, making them particularly effective in treating joint disorders such as osteoarthritis, cartilage injuries, bone necrosis, and tendinopathies.

Can’t wait to get your life back?

How?

It’s easier than you think. Discover the world’s most advanced Stem Cell and Exosomes treatment. Reach out to us — we’re here for you and happy to answer any questions you may have.

Where?

Como (Italy)
Milano (Italy)
Rome (Italy)
Varese (Italy)
Falciano (RSM)

A cutting-edge Mesenchymal Stem Cell Therapy for:

The procedure is specifically targeted at orthopedic problems ailing the shoulder, hip, knee, ankle, and other joints in the body:

  • Osteoarthritis

  • Conditions associated with inflammation and tissue damage

  • Cartilage degeneration

  • Bone fractures or non-unions

  • Tendon or ligament injuries

  • Avascular necrosis

  • Avascular necrosis

  • Cartilage injuries

Conventional Treatments offer temporary, symptom-focused relief only. Here’s why:

DRUGS

Pharmaceutical treatments target only symptoms—such as pain—without addressing the root causes. Moreover, they often come with serious medium- and long-term side effects (e.g., corticosteroids), which can accelerate joint degeneration and ultimately lead to surgical interventions such as joint replacement.

HYALURONIC ACID

While it improves joint lubrication and provides short-term relief, it does not halt the degenerative process. As a result, patients are often subjected to an ongoing cycle of palliative treatments.

While hyaluronic acid provides temporary (and progressively diminishing) relief by improving joint lubrication, MSCs offer long-term benefits by altering the course of the disease through their regenerative action.

PRP

PLATELET-RICH PLASMA

Though often marketed as a regenerative medicine product, PRP has no true regenerative function. It contains growth factors that temporarily stimulate the injected area but do not regenerate damaged tissues.
Expanded MSCs have a significantly greater capacity to regenerate cartilage than PRP or SVF, due to their ability to differentiate into chondrocytes that can repair and renew damaged tissue.

SVF

(STROMAL VASCULAR FRACTION – CENTRIFUGED FAT)

Regardless of the method used for its extraction, SVF offers no therapeutic benefit and often worsens inflammation, especially in joints, due to the high content of macrophages that trigger inflammatory responses. Moreover, the number of stem cells present in SVF is inadequate—only a few thousand cells—while effective treatment requires tens of millions.
Expanded MSCs, cultured and tested under controlled conditions, provide a significantly higher therapeutic cell dose, with a superior safety profile and lower risk of adverse reactions compared to heterogeneous, unquantified products like SVF.

Long-Term Benefits and Reduced Treatment Frequency

Thanks to their ability to induce meaningful and lasting biological changes, expanded MSC (Mesenchymal Stem Cell) injections require fewer sessions than conventional treatments like hyaluronic acid or SVF. Their regenerative capacity and standardization make them a more reliable and scientifically sound approach for treating degenerative conditions.

Contact us Today

Why?

Because you deserve to feel great again. To feel like yourself. The solution exists — it’s real, and it starts with your choice.

Where?

Como (Italy)
Milano (Italy)
Rome (Italy)
Varese (Italy)
Falciano (RSM)

How do Mesenchymal Stem Cells work?

Mesenchymal stem cells replace damaged/old musculoskeletal cells: Chondrocytes (cartilage cells), Osteoblasts (bone cells) and Tenocytes (tendon cells).

  • Tissue Regeneration
    The new and youthful, Chondrocytes, Osteoblasts and Tenocytes, produce the new cartilage, bone and tendon needed to avoid the degenerative processes.

  • Inflammation Modulation
    Mesenchymal Stem Cells have a powerful immunomodulatory effect that reduces pain and inflammation within the joint, providing symptomatic relief and improving mobility.

  • Secretion of Trophic Factors
    Mesenchymal Stem Cells promote healing and tissue regeneration through the secretion of growth factors and cytokines that stimulate the repair and regeneration of surrounding tissues.

  • Prevention of further Degeneration
    Mesenchymal Stem Cells slow down or sometimes prevent the progression of degenerative diseases through their ability to remodel and strengthen connective tissue.

Mesenchymal stem cells are the only treatment capable of achieving this result by addressing the root causes and not just its symptoms.
The second mechanism of action is to secrete exosomes that modulate the behavior of resident musculoskeletal cells boosting self-renewal and regeneration.

Expected Timeline

  • Week 1–2: Initial Phase
    Mild soreness or swelling at the injection site. No immediate improvement in joint symptoms.

  • Week 3–6: Onset of Improvement
    Gradual reduction in pain and stiffness. Improved range of motion. Early signs of reduced inflammation in RA patients.

  • Month 2–4: Peak of Symptomatic Relief
    Significant pain relief for many patients. Improved joint function. Enhanced daily activity capacity.

  • Month 5–12: Stabilization / Maintenance
    Sustained improvement in most responders. A possible booster injection may be considered in some protocols.

The Stem Cell Source

Mesenchymal stem cells are the same regardless of whether they are derived from Adipose Tissue or Umbilical Cord Tissue. The only difference lies in their biological age, which reflects the age of the tissue of origin.

Adipose Tissue Derived Stem Cells 

The treatment requires a fat collection, stem cell extraction, and expansion. The entire process takes approximately 2–3 weeks. Therefore, from the moment of fat harvesting, a waiting period of 2–3 weeks is necessary before the treatment can be performed.

Umbilical Cord Tissue derived Stem Cells

The treatment does not require fat harvesting and can be performed within 2–3 days of the request.

Stem Cell Procedure

Let’s clarify with accurate information:

Stem Cells obtained from a fat sample require at least two weeks of processing before they can be used; otherwise, the treatment is ineffective and potentially harmful:

  • Fat that is harvested and manipulated for use in the same session is both useless and harmful.
  • There are no Stem Cells in the blood, so treatments claiming to use stem cells extracted from blood are not scientifically valid. The Stem Cells used to treat hematological diseases are found in the bone marrow, not in the blood.
  • The hematopoietic stem cells found in umbilical cord blood are useful for treating blood disorders, but not for counteracting the aging processes of the human body

Realistic Expectations

  • Reduce joint pain and inflammation

  • Greater mobility and less stiffness

  • Stimulate some degree of cartilage repair

SC therapy is a promising regenerative and anti-inflammatory approach.  It can improve quality of life, reduce symptoms, and slow progression, but the outcomes depend on patient selection and disease stage. For this reason, a CONSULTATION WITH AN ORTHOPEDIC SPECIALIST IS ESSENTIAL.

Why Orthopedic Physicians choose MSC Therapy first?

Addressing Degenerative Joint and Bone Conditions at the Root Orthopedic medicine is rapidly evolving—from symptom management to true regeneration.
Today, Mesenchymal Stem Cells (MSCs) represent the most scientifically advanced and ethically responsible treatment for cartilage and bone degeneration.

Regenerative Medicine Respects the Cause, Not Just the Consequences

Conventional treatments such as corticosteroids, hyaluronic acid, painkillers, or even early surgical procedures only suppress symptoms like inflammation or pain—while the underlying degeneration silently progresses.
MSC therapy works differently: it promotes true repair by stimulating cartilage regeneration, reducing inflammation, and slowing structural deterioration.
A physician’s ethical duty is to treat the cause, not just cover it up.

Medical Responsibility Means Preserving Native Tissue

In orthopedics, delaying or avoiding joint replacement is always preferable—especially in younger patients.
MSCs help preserve native cartilage, improve joint function, and reduce reliance on invasive procedures.
From a professional standpoint, conserving tissue and preventing disability is a higher standard of care.

Long-Term Relief, Not Repeated Injections

Painkillers and steroids may offer fast relief but require frequent repetition, with cumulative toxicity and long-term joint damage.
MSC therapy, by contrast, often requires fewer sessions and provides sustained benefits.
Repeated symptomatic treatments without addressing the biological damage may be convenient—but not ethical.

Biocompatible, Non-Toxic, and Genotoxicity-Free

MSC treatments—especially when autologous—carry minimal risk of immune reaction or side effects. Unlike corticosteroids or NSAIDs, they do not harm the body over time.
Choosing the safest therapeutic option is both a clinical and ethical imperative.

Leading the Shift Toward Regenerative Orthopedics

MSC therapy is not an experimental approach—it is supported by robust clinical evidence and is already transforming how orthopedic degeneration is treated.
Ethical leadership means guiding patients toward innovative, evidence-based care—not waiting for outdated standards to change.
An orthopedic specialist committed to professional excellence and patient well-being cannot ignore the clinical superiority and biological intelligence of stem cell–based therapies.
Choosing MSCs first is not only scientifically justified—it is ethically necessary.

Learn how Stem Cells and Exosomes can change your life!

When?

Today! Reach out to us with confidence and discover the world’s most innovative solutions for Osteoarticular Regeneration. Our experts are here for you — ready to provide all the information and support you need to feel like yourself again.

Where?

Como (Italy)
Milano (Italy)
Rome (Italy)
Varese (Italy)
Falciano (RSM)

Stromal Vascular Fraction (SVF) VS Mesenchymal Stem Cells (MSC)

In the regenerative medicine landscape, many providers offer therapies labeled as "Stem Cell treatments" that utilize Stromal Vascular Fraction (SVF)—a heterogeneous mix of cells extracted from adipose tissue. While SVF contains some Stem Cells, it also includes various other cell types, leading to variability in treatment outcomes.
At our Clinic, we prioritize precision and efficacy by exclusively using Mesenchymal Stem Cells (MSCs). These are meticulously isolated and expanded in controlled laboratory settings, ensuring a pure, potent, and standardized cell population. This approach enhances the therapeutic potential and consistency of our treatments.

Standard Product and Therapy

MSC
YES, A pharma-grade product derived from a cell isolation and culture process, subject to strict quality control procedures

SVF
NO, Composition varies based on the collection site, the patient’s biological age, the digestion technique used, and several other factors.

Cellular Homogeneity

MSC
YES, Isolated and phenotyped cells

SVF
NO, Heterogeneous cell population

Concentration of MSC

MSC
100%

SVF
Between 0,001% and 0,01% of the total cells within

MSC per 10ml FAT

MSC
>100.000.000 after expansion

SVF
Around 9.000

Microphages per 10ml FAT

MSC
0 - Eliminated through isolation of MSCs

SVF
>400.000

Side Effects

MSC
NO

SVF
YES, often unpredictable, usually mediated by inflammatory processes caused by the macrophage population or potential bacterial contamination

Dosage

MSC
VARIOUS DOSAGES AVAILABLE
10-200 millions of MSC (based on indications)

SVF
SINGLE DOSAGE
not tailored to treatment

Safety

MSC
Pharma-grade production process, subjected to quality controls that ensure product sterility and biological safety

SVF
The production process is not monitorable and not subject to quality and biological safety controls

Treatments from 1 fat Collection

MSC
≥10

SVF
1

Phenotyping

MSC
YES

SVF
NO

Cellular Composition

MSC
Mesenchymal Stem Cells

SVF
Pericytes, Macrophages, Endothelial Cells, Mesenchymal Stem Cells, Adipocytes, Lymphocytes, Fibroblasts

Quality Control

MSC
Endotoxins, Mycoplasma, Anaerobic/Aerobic Bacteria, Viruses, Phenotype

SVF
None

Production Time

MSC
2-4 Weeks

SVF
1 hour

FDA Approval

MSC
YES (Ryoncil 18-12-2024)

SVF
NO

EMA Approval

MSC
YES (Alofisel, Spherox, Ryoncil)

SVF
NO

Usage

MSC
Autologous and Allogenic Localized and Systemic

SVF
Strictly Autologous, Homologous, and Localized

    POWERED BY

    BioScience Institute

    As the world’s leading center of Stem Cell and Regenerative Medicine, Bioscience offers unparalleled service and treatments, unique only to it. Bioscience offers the most advanced personalized expanded adipose derived Stem Cell therapies across Europe – including Rome, Milan, and San Marino, and the Middle East, including Dubai.

    The team at Bioscience Institute does not believe in using invasive surgeries when they can be partially replaced by cell biology. Therefore, they have designed an alternative method of extracting stem cells from adipose tissue. As a distinctive and versatile offering, adipose tissue provides an effective solution to all of Bioscience regenerative services, ranging from to hair loss treatments, to skin aging, to body reshaping treatments.

    Bioscience Institute Vision

    The beauty of regenerative medicine therapies and Stem Cell treatments comes from the ability to use your own body to help heal and enhance your well-being through living body tissue. Bioscience Institute’s vision is based on using this most effective and advanced Stem Cell treatments that is based on cell biology and Exosomes to help amplify our natural healing process in the areas it is needed most or take over the function of damaged tissue altogether.

    Stem cells verified treatments

    With the ability to develop methods to regrow, repair, or replace damaged cells and tissues, using Stem Cell & regenerative medicines provides a natural method of treatment that is less traumatic to the body and more effective than other more invasive treatments and surgeries. The stem cell therapies provided by Bioscience Institute are verified in Europe and the Middle East by scientific evidence of increased safety and efficiency than any other treatment method.

    Scientific Research

    The Bioscience’s profits are consistently reinvested into developing research. Avoiding a flashy commercial profile allows us to concentrate on using investments to create better treatments and ultimately help clients globally. Due to this commitment, Bioscience Institute has instigated important scientific collaborations with leading universities, pioneering procedures and methods around cell products.

    Bioscience Cell Factory and Clinic in Dubai, San Marino, Italy & Switzerland

    Bioscience Institute is the first and only GMP-certified Clinic in the Middle East and Europe, offering stem cell treatments with the most advanced personalized autologous cell therapies worldwide.
    Offering a unique service and treatment sets it apart from any form of competition and allows it to give clients the care, attention, and treatment they deserve.

    • Bioscience Clinics in the Middle East and Europe include a fully equipped facility needed to carry out any treatments offered, whether Stem Cell treatments or banking.
    • Bioscience Laboratory is a dedicated Cell Banking Factory used to store and expand Adipose-Derived Cells and Fibroblasts to help ensure that the clients’ needs can always and easily be catered to.