Why settle for Breast Implants when Safer, Smarter Options Exist?

With our Natural Breast Augmentation using your own fat and expanded Mesenchymal Stem Cells (MSCs), it’s now possible to achieve beautiful, long-lasting results, without the risks of synthetic implants.

Enhance your Breast's Volume in a completely Biocompatible Way

This approach enhances volume in a completely biocompatible, regenerative way that restores both aesthetics and tissue health, offering:

No foreign materials

No long-term complications

No need for replacement

A natural look and feel

Choosing a regenerative, Stem Cell–based alternative means prioritizing your safety, health, and natural beauty — today and for the future.

Breast Enhancement with Expanded Mesenchymal Stem Cells

Breast augmentation using Autologous Fat enriched with Expanded Mesenchymal Stem Cells (MSCs) offers a safe and natural alternative to traditional implants. In this advanced procedure, fat is harvested from the patient and combined with MSCs before being reinjected into the breast.

The presence of Mesenchymal Stem Cells significantly improves the long-term stability of the grafted volume. These cells promote vascularization, enhance tissue integration, and prevent the formation of necrotic tissue — a common complication when fat is injected without regenerative support. In conventional fat grafting, poor cell survival can lead to partial reabsorption of the fat and the formation of fibrotic or necrotic areas.

Thanks to the regenerative and anti-inflammatory properties of MSCs, the result is not only more durable but also aesthetically superior, with a soft, natural feel and contour that closely mimics the natural breast.
This technique is ideal for patients seeking a natural enhancement without the use of synthetic materials, while maintaining safety, tissue integrity, and long-term volume
retention.

Breast Enhancement with MSCs is superior to Breast Implants

Natural breast augmentation using autologous fat combined with expanded mesenchymal Stem Cells (MSCs) offers significant advantages over traditional breast implants — both in terms of safety and aesthetic outcome.

  • No Foreign Body - Reduced risk of Complications
    Unlike silicone or saline implants, fat grafting enriched with MSCs uses the patient’s own tissue. This eliminates the risks associated with foreign materials such as capsular contracture, implant rupture, leakage, or late immune reactions including Breast Implant Illness (BII) and Anaplastic Large Cell Lymphoma (BIA-ALCL).

  • Long-Term Volume Stability and Safety
    When fat is injected alone, part of it may be reabsorbed or undergo necrosis, leading to volume loss or the formation of hard nodules. MSCs enhance graft survival by promoting angiogenesis and reducing inflammation, resulting in more stable, long-lasting volume without necrotic areas.

  • Aesthetic Superiority - Natural Look and Feel
    Fat-based augmentation achieves a much more natural appearance and texture than implants. The breast maintains its natural softness and shape, without the unnatural roundness or stiffness that is sometimes seen with prostheses.

  • No Maintenance or Replacement Required
    Implants typically require revision or replacement every 10–15 years, exposing patients to repeated surgeries and additional risks. In contrast, MSC-enriched fat grafting is a regenerative, one-time procedure with no need for future implant replacement.

  • Regenerative Benefits Beyond Aesthetics
    MSCs have regenerative properties that improve the quality of surrounding tissues, stimulate local repair processes, and enhance skin texture and elasticity. This makes the procedure not only cosmetic, but also rejuvenating at the biological level.

  • Minimally Invasive with Faster Recovery
    Since the procedure uses gentle liposuction and injection techniques, it is less invasive than implant placement. Recovery is quicker, with lower risks of infection, scarring, or post- operative complications.

Conclusion: Traditional breast implants are associated with a range of mechanical and biological complications. Natural breast enhancement with fat and MSCs offers a safer, regenerative, and more natural alternative—transforming the concept of augmentation from artificial correction to biological restoration.

Can’t wait to have your skin back?

How?

It’s easier than you think. Discover the world’s most advanced Stem Cell and Exosomes treatment. Reach out to us — we’re here for you and happy to answer any questions you may have.

Where?

Como (Italy)
Milano (Italy)
Rome (Italy)
Varese (Italy)
Falciano (RSM)

The Best Solution for Natural Breast Augmentation

Breast augmentation with autologous fat enriched with Mesenchymal Stem Cells (MSCs) is an advanced, regenerative alternative to synthetic implants. This technique not
only enhances volume, but also improves tissue quality and ensures long-term, natural-looking results — without the risks associated with implants.
How It Works:

  • Fat Harvesting
    A small amount of fat is gently extracted from areas such as the abdomen or thighs using liposuction.

  • MSC Expansion and Enrichment
    Mesenchymal stem cells are isolated and expanded in a certified laboratory to achieve high purity and regenerative potency. These cells are then combined with the harvested fat before reinjection.

  • Targeted Injection into the Breast
    The fat–MSC mixture is carefully injected into the breast tissue, allowing for precise sculpting and volume enhancement.

The Limitations of Breast Implants - and why it's better to Avoid Them

While breast implants have long been used for cosmetic enhancement, they come with a number of risks and limitations that patients should carefully consider before undergoing surgery. Today, safer and more natural alternatives are available.

FOREIGN BODY REACTION

Breast implants are synthetic materials (silicone or saline) and can trigger an immune
response. Over time, the body may form a fibrous capsule around the implant, leading to
complications such as capsular contracture, which causes pain, distortion, and hardening of
the breast.

RISK OF RUPTURE OR LEAKAGE

Implants are not lifetime devices. They can rupture or leak—silicone gel may remain trapped
in the surrounding tissue or migrate, sometimes without immediate symptoms, potentially
requiring surgical removal.

UNNATURAL LOOK AND FEEL

Implants can sometimes be seen or felt under the skin, especially in lean individuals.
Rippling, asymmetry, or an overly round shape can result in an unnatural appearance, unlike
the soft, organic look of natural tissue.

ASSOCIATED HEALTH RISKS

Recent concerns have linked implants to conditions such as Breast Implant Illness (BII) and
a rare form of cancer known as BIA-ALCL (Breast Implant-Associated Anaplastic Large Cell
Lymphoma), raising long-term safety concerns.

INTERFERENCE WITH MEDICAL IMAGING

Breast implants can obscure mammography results, making early detection of breast cancer
more challenging and reducing the accuracy of routine breast screening.

Why MSCs make the Difference

Mesenchymal stem cells dramatically improve the success and safety of fat grafting through their unique biological properties:

  • Enhanced Graft Survival
    MSCs promote the formation of new blood vessels (angiogenesis), which ensures better oxygen and nutrient supply to the grafted fat. This reduces fat reabsorption and prevents volume loss over time.

  • Prevention of Necrosis and Fibrosis
    When fat is injected without MSCs, parts of it may not integrate properly, leading to the formation of necrotic tissue or fibrotic lumps. MSCs prevent this by promoting healthy tissue regeneration and modulating inflammation.

  • Natural Regeneration of Tissue
    MSCs release bioactive molecules that stimulate repair and rejuvenation of surrounding tissues, improving skin quality, elasticity, and overall breast appearance.

  • Safe and Biocompatible
    Since both the fat and the MSCs come from the patient's own body, the procedure is 100% biocompatible and carries no risk of immune rejection or foreign body reaction.

The Result

  • Long-lasting, stable volume
  • Soft, natural shape and texture
  • No implants, no synthetic materials, no foreign body complications
  • No need for replacement or future surgeries
  • Enhanced tissue health and regeneration

Conclusion

Thanks to the regenerative power of mesenchymal stem cells, fat grafting becomes not just a cosmetic procedure, but a biological restoration. For women seeking safe, natural, and lasting breast enhancement, FAT + MSCs is the most advanced and effective solutionavailable today.

Contact us Today

Why?

Because you deserve to feel young, beautiful, and self confident again. The solution exists — it’s real, and it starts with your choice.

Where?

Como (Italy)
Milano (Italy)
Rome (Italy)
Varese (Italy)
Falciano (RSM)

Fat Alone is not enough for Breast Augmentation

While autologous fat transfer is a popular technique for natural breast augmentation, fat alone is not sufficient to guarantee long-term results. Without proper biological support, fat grafts often fail to survive, leading to poor outcomes. When fat is injected into the breast without the support of stem cells:

  • Up to 60–80% of the injected fat is reabsorbed by the body within the first 3 - 4 months. This results in significant loss of volume and the need for repeated procedures.
  • Poor vascularization means the transplanted fat doesn’t receive enough oxygen and nutrients to survive, especially in larger volumes.
  • This leads to tissue necrosis, the formation of oil cysts, calcifications, and fibrotic nodules, which compromise both the appearance and the safety of the result.
  • Radiological follow-ups may become confusing due to these complications, which can mimic pathological findings.

The Role of Expanded Mesenchymal Stem Cells (MSCs)

To overcome these limitations, the fat must be combined with expanded Mesenchymal Stem Cells:

  • MSCs enhance graft survival by promoting the development of new blood vessels (angiogenesis), ensuring that the fat remains nourished and integrated into the
    tissue.
  • They prevent necrosis and cyst formation by modulating inflammation and stimulating natural tissue repair.
  • Expanded MSCs, unlike those found in small amounts in unprocessed fat or stromal vascular fraction (SVF), are purified and amplified in a laboratory to achieve high therapeutic potency.

The Result

  • Volume retention is stable and long-lasting
  • The risk of complications such as necrosis and cysts is drastically reduced
  • The result is natural in both appearance and feel
  • No need for repeated interventions

Conclusion

Fat alone is not enough. Without expanded mesenchymal stem cells, fat grafting is
unreliable, short-lived, and often leads to complications. Combining fat with MSCs transforms the procedure into a safe, regenerative, and effective solution - the new gold standard in natural breast augmentation.

The Stem Cell Source

Mesenchymal stem cells are the same regardless of whether they are derived from Adipose Tissue or Umbilical Cord Tissue. The only difference lies in their biological age, which reflects the age of the tissue of origin.

Adipose Tissue Derived Stem Cells 

The treatment requires a fat collection, stem cell extraction, and expansion. The entire process takes approximately 2–3 weeks. Therefore, from the moment of fat harvesting, a waiting period of 2–3 weeks is necessary before the treatment can be performed.

Umbilical Cord Tissue derived Stem Cells

The treatment does not require fat harvesting and can be performed within 2–3 days of the request.

Stem Cell Procedure

Let’s clarify with accurate information:

Stem Cells obtained from a fat sample require at least two weeks of processing before they can be used; otherwise, the treatment is ineffective and potentially harmful:

  • Fat that is harvested and manipulated for use in the same session is both useless and harmful.
  • There are no Stem Cells in the blood, so treatments claiming to use stem cells extracted from blood are not scientifically valid. The Stem Cells used to treat hematological diseases are found in the bone marrow, not in the blood.
  • The hematopoietic stem cells found in umbilical cord blood are useful for treating blood disorders, but not for counteracting the aging processes of the human body

What to Expect from Mesenchymal Stem Cell (MSC) Treatment for Breast Augmentation

Breast augmentation using your own fat enriched with expanded Mesenchymal Stem Cells (MSCs) delivers natural, long-lasting, and regenerative results—without the risks and complications associated with implants.

  • Naturally Beautiful Shape and Volume
    The procedure provides a soft, symmetrical, and natural-looking enhancement of the breast contour. Since the fat comes from your own body and is carefully sculpted, the result is harmonious with your natural anatomy - unlike the artificial roundness of implants.

  • Long-Lasting Volume Retention
    Thanks to the regenerative power of MSCs, up to 80 - 90% of the injected volume is permanently retained. The stem cells promote the formation of new blood vessels that support and nourish the transplanted fat, ensuring durability over time.

  • No Hard Nodules or Necrosis
    Unlike traditional fat grafting, which often leads to partial reabsorption, oil cysts, or fat necrosis, the presence of expanded MSCs ensures stable integration into the tissue without complications.

  • Soft, Natural Feel
    The enhanced breast tissue maintains its natural softness and mobility, indistinguishable from native breast tissue to the touch - something that cannot be achieved with implants.

  • Improved Skin Quality
    MSCs have anti-inflammatory and regenerative effects that rejuvenate the skin, improving its elasticity, texture, and firmness in the treated area.

  • Dual Benefit: Body Contouring + Breast Enhancement
    Because fat is harvested from areas like the abdomen, thighs, or flanks, patients also enjoy the added benefit of body contouring, enhancing their overall silhouette.

Final Result

  • A fuller, more youthful breast appearance
  • Natural shape and movement
  • No implants, no scars, no foreign materials
  • Long-lasting outcome with minimal risk
  • Rejuvenated, healthier tissue

Conclusion

Breast augmentation with fat and MSCs is not just cosmetic - it’s regenerative.
It’s the most advanced, safe, and natural solution for women seeking enhancement without compromising their health or aesthetic integrity.

Step by Step

Natural breast augmentation with fat and expanded mesenchymal stem cells (MSCs) is a cutting-edge, regenerative procedure that enhances volume, shape, and tissue quality - without the need for implants. Here’s how it works, step by step:
  • Step 1: Fat Harvesting
    A small amount of fat is gently removed from areas such as the abdomen, thighs, or flanks using minimally invasive liposuction. This process not only provides the material for breast augmentation but also offers the added benefit of body contouring.

  • Step 2: Isolation and Expansion of MSCs
    Mesenchymal stem cells are isolated from a small sample of the patient’s fat or umbilical cord tissue (if using donor-derived cells). These cells are then expanded in a certified laboratory to achieve high purity, concentration, and regenerative potency.
    Note: Only expanded MSCs ensure the therapeutic effectiveness needed to stabilize and regenerate the fat graft.

  • Step 3: Enrichment of the Fat with MSCs
    The harvested fat is then combined with the expanded MSCs, creating a biologically active mixture. This enriched fat is far more likely to survive and integrate naturally into the breast tissue.

  • Step 4: Precise Fat–MSC Injection into the Breast
    Using microcannulas, the enriched fat is carefully and strategically injected into different layers of the breast to sculpt the desired shape and volume. The technique ensures even distribution, smooth contours, and natural symmetry.

  • Step 5: Regeneration and Volume Stabilization
    Once injected, the MSCs play a key role:

    • They promote angiogenesis (formation of new blood vessels), which ensures that the fat cells receive adequate oxygen and nutrients.
    • They reduce inflammation and prevent tissue necrosis or the formation of oil cysts.
    • They stimulate natural tissue regeneration, improving skin elasticity, tone, and structural integrity.

Outcome

  • Natural-looking and feeling breast enhancement
  • Stable, long-lasting volume retention
  • No risk of rejection or foreign body complications
  • Regenerative effects on surrounding tissue
This procedure is not simply aesthetic—it is biological rejuvenation.
By combining fat with expanded MSCs, we transform breast augmentation into a safe, effective, and regenerative solution that respects and enhances your body’s natural harmony.

Learn how Stem Cells and Exosomes can change your life!

When?

Today! Reach out to us with confidence and discover the world’s most innovative solutions for Breast Augmentation. Our experts are here for you — ready to provide all the information and support you need to feel like yourself again.

Where?

Como (Italy)
Milano (Italy)
Rome (Italy)
Varese (Italy)
Falciano (RSM)

Stromal Vascular Fraction (SVF) VS Mesenchymal Stem Cells (MSC)

In the regenerative medicine landscape, many providers offer therapies labeled as "Stem Cell treatments" that utilize Stromal Vascular Fraction (SVF)—a heterogeneous mix of cells extracted from adipose tissue. While SVF contains some Stem Cells, it also includes various other cell types, leading to variability in treatment outcomes.
At our Clinic, we prioritize precision and efficacy by exclusively using Mesenchymal Stem Cells (MSCs). These are meticulously isolated and expanded in controlled laboratory settings, ensuring a pure, potent, and standardized cell population. This approach enhances the therapeutic potential and consistency of our treatments.

Standard Product and Therapy

MSC
YES, A pharma-grade product derived from a cell isolation and culture process, subject to strict quality control procedures

SVF
NO, Composition varies based on the collection site, the patient’s biological age, the digestion technique used, and several other factors.

Cellular Homogeneity

MSC
YES, Isolated and phenotyped cells

SVF
NO, Heterogeneous cell population

Concentration of MSC

MSC
100%

SVF
Between 0,001% and 0,01% of the total cells within

MSC per 10ml FAT

MSC
>100.000.000 after expansion

SVF
Around 9.000

Microphages per 10ml FAT

MSC
0 - Eliminated through isolation of MSCs

SVF
>400.000

Side Effects

MSC
NO

SVF
YES, often unpredictable, usually mediated by inflammatory processes caused by the macrophage population or potential bacterial contamination

Dosage

MSC
VARIOUS DOSAGES AVAILABLE
10-200 millions of MSC (based on indications)

SVF
SINGLE DOSAGE
not tailored to treatment

Safety

MSC
Pharma-grade production process, subjected to quality controls that ensure product sterility and biological safety

SVF
The production process is not monitorable and not subject to quality and biological safety controls

Treatments from 1 fat Collection

MSC
≥10

SVF
1

Phenotyping

MSC
YES

SVF
NO

Cellular Composition

MSC
Mesenchymal Stem Cells

SVF
Pericytes, Macrophages, Endothelial Cells, Mesenchymal Stem Cells, Adipocytes, Lymphocytes, Fibroblasts

Quality Control

MSC
Endotoxins, Mycoplasma, Anaerobic/Aerobic Bacteria, Viruses, Phenotype

SVF
None

Production Time

MSC
2-4 Weeks

SVF
1 hour

FDA Approval

MSC
YES (Ryoncil 18-12-2024)

SVF
NO

EMA Approval

MSC
YES (Alofisel, Spherox, Ryoncil)

SVF
NO

Usage

MSC
Autologous and Allogenic Localized and Systemic

SVF
Strictly Autologous, Homologous, and Localized

    POWERED BY

    BioScience Institute

    As the world’s leading center of Stem Cell and Regenerative Medicine, Bioscience offers unparalleled service and treatments, unique only to it. Bioscience offers the most advanced personalized expanded adipose derived Stem Cell therapies across Europe – including Rome, Milan, and San Marino, and the Middle East, including Dubai.

    The team at Bioscience Institute does not believe in using invasive surgeries when they can be partially replaced by cell biology. Therefore, they have designed an alternative method of extracting stem cells from adipose tissue. As a distinctive and versatile offering, adipose tissue provides an effective solution to all of Bioscience regenerative services, ranging from to hair loss treatments, to skin aging, to body reshaping treatments.

    Bioscience Institute Vision

    The beauty of regenerative medicine therapies and Stem Cell treatments comes from the ability to use your own body to help heal and enhance your well-being through living body tissue. Bioscience Institute’s vision is based on using this most effective and advanced Stem Cell treatments that is based on cell biology and Exosomes to help amplify our natural healing process in the areas it is needed most or take over the function of damaged tissue altogether.

    Stem cells verified treatments

    With the ability to develop methods to regrow, repair, or replace damaged cells and tissues, using Stem Cell & regenerative medicines provides a natural method of treatment that is less traumatic to the body and more effective than other more invasive treatments and surgeries. The stem cell therapies provided by Bioscience Institute are verified in Europe and the Middle East by scientific evidence of increased safety and efficiency than any other treatment method.

    Scientific Research

    The Bioscience’s profits are consistently reinvested into developing research. Avoiding a flashy commercial profile allows us to concentrate on using investments to create better treatments and ultimately help clients globally. Due to this commitment, Bioscience Institute has instigated important scientific collaborations with leading universities, pioneering procedures and methods around cell products.

    Bioscience Cell Factory and Clinic in Dubai, San Marino, Italy & Switzerland

    Bioscience Institute is the first and only GMP-certified Clinic in the Middle East and Europe, offering stem cell treatments with the most advanced personalized autologous cell therapies worldwide.
    Offering a unique service and treatment sets it apart from any form of competition and allows it to give clients the care, attention, and treatment they deserve.

    • Bioscience Clinics in the Middle East and Europe include a fully equipped facility needed to carry out any treatments offered, whether Stem Cell treatments or banking.
    • Bioscience Laboratory is a dedicated Cell Banking Factory used to store and expand Adipose-Derived Cells and Fibroblasts to help ensure that the clients’ needs can always and easily be catered to.