Losing skin firmness, smoothness, and youthful glow? Leard about the real Collagen and Elastin factories.

Our treatment boosts the facial’s natural healing: the skin will rebuild itself in a natural, healthy way from the inside out, increasing skin collagen by up to six-fold and, elastin levels by up to 300%.

Forget about the limits of Botox, Fillers and PRP.

Stem Cell represent a breakthrough in Skin Rejuvenation, going beyond the temporary effects of Hyaluronic Acid, Botox, and even PRP. While these traditional treatments focus on filling, relaxing, or stimulating superficially, Stem Cells activate deep cellular regeneration. They boost collagen and elastin production, improving skin firmness, texture, and radiance from within—addressing the root causes of aging for lasting results. The results of conventional treatments often lead to wrinkle-free skin that still looks old because it lacks collagen and elasticity, resulting in a very unnatural appearance.

These signs of aging can be effectively reversed with Stem Cell Treatments that target the root causes — not just the symptoms

  • Fine lines and/or wrinkles

  • Loss of firmness and elasticity

  • Thinner, more fragile skin

  • Dryness and rough texture

  • Enlarged pores

  • Visible capillaries or redness

  • Sagging around the eyes, jawline, and cheeks

How MSCs Work in Skin Rejuvenation

As we age, these cells (fibroblasts and keratinocytes) also age and no longer produce sufficient amounts of Collagen and Elastin.
This initially leads to the formation of fine lines and an aged texture, and as aging progresses, deeper wrinkles appear Mesenchymal stem cells replace damaged/old skin cells (fibroblast and keratinocytes). The new and youthful fibroblasts and keratinocytes, once present in the skin, produce the collagen and elastin needed to maintain a youthful appearance. Mesenchymal stem cells are the only treatment capable of achieving this result by addressing the root causes of aging, not just its symptoms.The  second mechanism of action is to secrete exosomes that modulate the behavior of resident skin cells boosting self-renewal and regeneration.

This is the World Class regenerative treatment for Skin Aging

A natural, personalized skin‑rejuvenation treatment that uses the Stem Cells to awaken your skin’s inner vitality. It harnesses the power of Collagen and Elastin—those molecules that differentiate youthful, glowing skin from time-worn texture. With no artificial fillers or toxins, this method rejuvenates the skin from within, celebrating the authenticity of your natural beauty. Mesenchymal stem cell work at the root cause—not just on the surface - because it addresses the causes of aging, not just the symptoms. MSC-based treatments aim to reverse or slow the aging process at the cellular level by stimulating tissue repair and regeneration.

Can’t wait to have your skin back?

How?

It’s easier than you think. Discover the world’s most advanced Stem Cell and Exosomes treatment. Reach out to us — we’re here for you and happy to answer any questions you may have.

Where?

Como (Italy)
Milano (Italy)
Rome (Italy)
Varese (Italy)
Falciano (RSM)

The main difference between a newborn's and elderly person's skin is the concentration of Mesenchymal Stem Cells they contain.

While a newborn's wound heals in hours, an elderly person's may take weeks. This demonstrates that aging is fundamentally caused by stem cell depletion in organs and tissues, impairing their regenerative capacity.
The only effective way to combat the relentless processes of skin aging at their root cause — rather than merely addressing the symptoms — is regenerative medicine, which works by increasing the number of stem cells. This breakthrough treatment utilizes powerful mesenchymal stem cells, which can be sourced either from adipose (fat) tissue or umbilical cord tissue, with no significant difference in efficacy or compatibility. To achieve the most youthful biological condition possible, there are only two exclusive approaches:

Adipose Tissue Derived Stem Cells 

The treatment requires a fat collection, stem cell extraction, and expansion. The entire process takes approximately 2–3 weeks. Therefore, from the moment of fat harvesting, a waiting period of 2–3 weeks is necessary before the treatment can be performed.

Umbilical Cord Tissue derived Stem Cells

The treatment does not require fat harvesting and can be performed within 2–3 days of the request.

Stem Cell Procedure

Let’s clarify with accurate information:

Stem Cells obtained from a fat sample require at least two weeks of processing before they can be used; otherwise, the treatment is ineffective and potentially harmful:

  • Fat that is harvested and manipulated for use in the same session is both useless and harmful.
  • There are no Stem Cells in the blood, so treatments claiming to use stem cells extracted from blood are not scientifically valid. The Stem Cells used to treat hematological diseases are found in the bone marrow, not in the blood.
  • The hematopoietic stem cells found in umbilical cord blood are useful for treating blood disorders, but not for counteracting the aging processes of the human body

What to Expect from Mesenchymal Stem Cell (MSC) Treatment for Skin Aging

Mesenchymal stem cells (MSCs) offer a regenerative approach to skin aging, going beyond superficial results. Here’s what patients can typically expect from MSC-based treatments:

  • Reduction of Fine Wrinkles
    MSCs stimulate collagen and elastin production, leading to visible softening of fine lines and expression wrinkles, especially around the eyes and mouth.

  • Improvement in Skin Texture
    Treated skin becomes smoother, more hydrated, and evenly toned. MSCs help repair micro-damage, enhance dermal density, and restore a youthful, luminous appearance.

  • Reduction in Deep Wrinkles
    While deep wrinkles are more structurally rooted, MSCs promote dermal regeneration and gradual skin thickening, which can reduce the depth and harshness of these folds over time.

  • Progressive and Natural Results
    Unlike fillers or Botox, MSCs do not simply mask the signs of aging—they help reverse them by supporting the skin’s own regenerative capacity. Results improve progressively over weeks to months.

  • Long-Lasting Benefits
    With proper skin care and lifestyle habits, the rejuvenating effects of MSCs can last longer than conventional treatments, reducing the need for frequent touch-ups.

MSC treatments are particularly effective when integrated into a broader longevity or regenerative medicine protocol, tailored to each individual's skin biology.

Contact us Today

Why?

Because you deserve to feel young, beautiful, and self confident again. The solution exists — it’s real, and it starts with your choice.

Where?

Como (Italy)
Milano (Italy)
Rome (Italy)
Varese (Italy)
Falciano (RSM)

Smooth but aged: wrinkle-free skin achieved through Botox and fillers doesn’t mean younger skin — only the appearance has changed, but it’s still biologically old

Collagen and Elastin are proteins that differentiate a child’s skin from that of an adult. Notably, Collagen cannot be synthetically replicated: only skin cells are capable of
producing it. We harness the power of Mesenchymal Stem Cells to stimulate the natural production of those 2 proteins. A natural, regenerative approach that avoids injecting artificial substances into the skin.

Delivery method of Stem Cell for Skin Aging (fine wrinkles, texture and deep wrinkles)

To effectively target different signs of skin aging—such as fine lines, uneven texture, and deep wrinkles—stem cells can be delivered using the following advanced methods:

Microinjection

Ideal for treating fine lines and improving skin texture. Stem cells are injected in very small quantities into the superficial dermal layers using ultra-fine needles for precise, localized rejuvenation.

Mesotherapy

Multi-puncture Technique
A series of microinjections across broader areas of the face deliver stem cells into the middle layer of the skin. This technique helps improve overall skin tone, elasticity, and surface texture.

ï‚· Cannula Injection

Used to treat deeper wrinkles and volume loss. A blunt-tip cannula allows for safer and more uniform distribution of stem cells into the deeper dermis or subdermal layers, minimizing trauma and enhancing regenerative effects.

Combined Approach

For optimal results, a personalized combination of techniques is often used to address the full spectrum of aging signs—from fine surface lines to structural wrinkles.

Combination with other therapies

While treatments like Botox and Fillers can reduce the appearance of wrinkles, they do not improve the underlying quality of the skin.
Combining regenerative therapy with Botox or Fillers enhance Collagen thickness, so the skin not only appears smoother but also visibly healthier and younger. This prevents the paradox of wrinkle-free skin that still looks aged.

Expected Timeline

  • Immediate/2 weeks
    Mild improvement in skin brightness and texture. Early reduction in fine wrinkles and pores.

  • 4–6 weeks
    Noticeable softening of fine lines and improved skin elasticity. Decreased pigmentation spots and a more luminous, even tone.

  • 8–12 weeks
    Reduction in moderate-to-deep wrinkles begins, supported by increased collagen and elastin synthesis. Enhanced dermal thickness and better structure - especially when MSCs are used alongside microneedling or fillers.

  • 3–6 months
    Sustained improvement in most responders A possible booster injection may be considered in some protocols.

  • 6+ months
    Long-term benefits stabilize: fewer touch-ups needed if healthy lifestyle and skincare habits are maintained. MSCs work at a fundamental level - supporting skin’s own repair mechanisms - unlike temporary fillers.

Why MSC Treatments save you money compared to conventional ones?

Mesenchymal stem cell (MSC) therapy may appear more expensive upfront - but it actually helps you save money over time by targeting the root causes of aging and reducing the need for frequent maintenance. It helps you avoid the high cumulative cost of frequent, symptom-focused treatments by offering real, regenerative, and lasting results.

  • Regenerative, Not Temporary
    Unlike Botox, fillers, PRP, or hyaluronic acid—which only offer short-term relief—MSCs promote true biological rejuvenation by stimulating collagen, elastin, and skin repair.

  • Fewer sessions, longer-lasting results - Reduced Need for Repetitive Treatments
    Most conventional treatments require frequent top-ups every 1–3 months to maintain their effects.
    MSC therapy, on the other hand, provides visible improvements for 6–12 months or more, especially when part of a personalized anti-aging plan.

  • You spend less over time - One Treatment = Multiple Benefits
    A single MSC session can simultaneously improve:
    • Fine lines
    • Skin texture
    • Deep wrinkles
    • Hydration and elasticity
    • Dermal density and glow
    You avoid combining multiple treatments to achieve similar outcomes.

  • Slows Down Aging Progression
    By addressing the biological mechanisms of aging, MSCs delay the need for more aggressive interventions like surgery or repeated fillers.
    A smarter, long-term investment in your skin.

MSC treatments are particularly effective when integrated into a broader longevity or regenerative medicine protocol, tailored to each individual's skin biology.

Why Ethical and Forward-Thinking Physicians choose MSC Therapy first?

For any medical professional, the primary duty is to offer patients safe, effective, and scientifically grounded solutions. When it comes to treating skin aging, mesenchymal stem cells (MSCs) represent the most advanced and responsible approach available today.

Treating the cause, non just the symptoms

Conventional treatments act only on the surface - temporarily masking the signs of aging without addressing the biological deterioration of the skin.
MSCs, by contrast, regenerate and restore the skin's structure and function at a cellular level.
Offering true healing over short-lived camouflage is a professional responsibility.

Supporting the body's natural repair mechanisms

MSC therapy activates the skin’s own regenerative processes—promoting collagen production, improving vascularization, and restoring tissue vitality.
This aligns with the physician’s ethical obligation to support physiological balance and natural healing.

Science-Driven, not Trend-Driven

Choosing MSCs means embracing the most scientifically validated and biologically intelligent solution—rather than relying on outdated or purely cosmetic trends.
An ethical doctor should offer what’s best, not what’s simply popular.

Minimizing Patient risk and long-term harm

Repeated use of conventional injectables can lead to tissue fatigue, irregular facial volumes, or dependence on corrective procedures.
MSCs, being autologous or biocompatible, are non-toxic, non-genotoxic, and biologically integrative.
Doctors have a duty to “do no harm”—and that includes avoiding cumulative iatrogenic effects.

A shift toward Regenerative Aesthetic Medicine

The future of aesthetic medicine is regenerative, not palliative. MSCs offer long-term benefits that reduce dependency on invasive or repetitive treatments.
Being medically and ethically progressive means leading patients toward sustainable beauty, not temporary fixes.

Learn how Stem Cells and Exosomes can change your life!

When?

Today! Reach out to us with confidence and discover the world’s most innovative solutions for Skin Rejuvenation. Our experts are here for you — ready to provide all the information and support you need to feel like yourself again.

Where?

Como (Italy)
Milano (Italy)
Rome (Italy)
Varese (Italy)
Falciano (RSM)

Stromal Vascular Fraction (SVF) VS Mesenchymal Stem Cells (MSC)

In the regenerative medicine landscape, many providers offer therapies labeled as "Stem Cell treatments" that utilize Stromal Vascular Fraction (SVF)—a heterogeneous mix of cells extracted from adipose tissue. While SVF contains some Stem Cells, it also includes various other cell types, leading to variability in treatment outcomes.
At our Clinic, we prioritize precision and efficacy by exclusively using Mesenchymal Stem Cells (MSCs). These are meticulously isolated and expanded in controlled laboratory settings, ensuring a pure, potent, and standardized cell population. This approach enhances the therapeutic potential and consistency of our treatments.

Standard Product and Therapy

MSC
YES, A pharma-grade product derived from a cell isolation and culture process, subject to strict quality control procedures

SVF
NO, Composition varies based on the collection site, the patient’s biological age, the digestion technique used, and several other factors.

Cellular Homogeneity

MSC
YES, Isolated and phenotyped cells

SVF
NO, Heterogeneous cell population

Concentration of MSC

MSC
100%

SVF
Between 0,001% and 0,01% of the total cells within

MSC per 10ml FAT

MSC
>100.000.000 after expansion

SVF
Around 9.000

Microphages per 10ml FAT

MSC
0 - Eliminated through isolation of MSCs

SVF
>400.000

Side Effects

MSC
NO

SVF
YES, often unpredictable, usually mediated by inflammatory processes caused by the macrophage population or potential bacterial contamination

Dosage

MSC
VARIOUS DOSAGES AVAILABLE
10-200 millions of MSC (based on indications)

SVF
SINGLE DOSAGE
not tailored to treatment

Safety

MSC
Pharma-grade production process, subjected to quality controls that ensure product sterility and biological safety

SVF
The production process is not monitorable and not subject to quality and biological safety controls

Treatments from 1 fat Collection

MSC
≥10

SVF
1

Phenotyping

MSC
YES

SVF
NO

Cellular Composition

MSC
Mesenchymal Stem Cells

SVF
Pericytes, Macrophages, Endothelial Cells, Mesenchymal Stem Cells, Adipocytes, Lymphocytes, Fibroblasts

Quality Control

MSC
Endotoxins, Mycoplasma, Anaerobic/Aerobic Bacteria, Viruses, Phenotype

SVF
None

Production Time

MSC
2-4 Weeks

SVF
1 hour

FDA Approval

MSC
YES (Ryoncil 18-12-2024)

SVF
NO

EMA Approval

MSC
YES (Alofisel, Spherox, Ryoncil)

SVF
NO

Usage

MSC
Autologous and Allogenic Localized and Systemic

SVF
Strictly Autologous, Homologous, and Localized

    POWERED BY

    BioScience Institute

    As the world’s leading center of Stem Cell and Regenerative Medicine, Bioscience offers unparalleled service and treatments, unique only to it. Bioscience offers the most advanced personalized expanded adipose derived Stem Cell therapies across Europe – including Rome, Milan, and San Marino, and the Middle East, including Dubai.

    The team at Bioscience Institute does not believe in using invasive surgeries when they can be partially replaced by cell biology. Therefore, they have designed an alternative method of extracting stem cells from adipose tissue. As a distinctive and versatile offering, adipose tissue provides an effective solution to all of Bioscience regenerative services, ranging from to hair loss treatments, to skin aging, to body reshaping treatments.

    Bioscience Institute Vision

    The beauty of regenerative medicine therapies and Stem Cell treatments comes from the ability to use your own body to help heal and enhance your well-being through living body tissue. Bioscience Institute’s vision is based on using this most effective and advanced Stem Cell treatments that is based on cell biology and Exosomes to help amplify our natural healing process in the areas it is needed most or take over the function of damaged tissue altogether.

    Stem cells verified treatments

    With the ability to develop methods to regrow, repair, or replace damaged cells and tissues, using Stem Cell & regenerative medicines provides a natural method of treatment that is less traumatic to the body and more effective than other more invasive treatments and surgeries. The stem cell therapies provided by Bioscience Institute are verified in Europe and the Middle East by scientific evidence of increased safety and efficiency than any other treatment method.

    Scientific Research

    The Bioscience’s profits are consistently reinvested into developing research. Avoiding a flashy commercial profile allows us to concentrate on using investments to create better treatments and ultimately help clients globally. Due to this commitment, Bioscience Institute has instigated important scientific collaborations with leading universities, pioneering procedures and methods around cell products.

    Bioscience Cell Factory and Clinic in Dubai, San Marino, Italy & Switzerland

    Bioscience Institute is the first and only GMP-certified Clinic in the Middle East and Europe, offering stem cell treatments with the most advanced personalized autologous cell therapies worldwide.
    Offering a unique service and treatment sets it apart from any form of competition and allows it to give clients the care, attention, and treatment they deserve.

    • Bioscience Clinics in the Middle East and Europe include a fully equipped facility needed to carry out any treatments offered, whether Stem Cell treatments or banking.
    • Bioscience Laboratory is a dedicated Cell Banking Factory used to store and expand Adipose-Derived Cells and Fibroblasts to help ensure that the clients’ needs can always and easily be catered to.