A New Era for Women’s Intimate Well-being: The real Vulvo-Vaginal Rejuvenation is here

Mesenchymal Stem Cells (MSCs) based regenerative therapies help renew comfort, function, and quality of life, offering lasting relief and restored confidence for your intimate health.

As a woman ages... the changes affect the cellular architecture, collagen matrix, and vascularization of the vaginal walls.

Over time, the intimate tissues can undergo profound changes that quietly affect comfort and well-being. The natural loss of Collagen and Elastin gradually robs the skin of its elasticity and firmness, while the thinning of the Epithelial Lining leaves it fragile and prone to micro-tears. Reduced Blood flow brings dryness and limits oxygenation, depriving the tissues of the nourishment they need to stay healthy. As Fibroblast activity declines, the production of vital structural proteins slows, weakening the very foundation of the tissue. Even the delicate Balance of the Microbiome and pH can be disrupted, raising the risk of irritation and infections.
Together, these changes can profoundly impact comfort, confidence, and quality of life — but emerging regenerative therapies offer hope for renewal and healing.

Top signs of Vaginal Aging

Vaginal dryness and lack of lubrication

Loss of elasticity or tightness

Thinning or fragility of the vaginal walls

Changes in vaginal pH (more prone to infections)

Loss of volume in the labia or pubic area

Reduced natural vaginal secretions

Vaginal Aging Symptoms

  • Painful intercourse (dyspareunia)

  • Vaginal burning, itching, or irritation

  • Frequent urinary tract infections (UTIs)

  • Urinary urgency, frequency, or incontinence

  • Discomfort during physical activity

Impact on Health and Daily Life

  • Mental health. Anxiety, embarrassment, or low self-esteem

  • Intimacy. Reduced sexual satisfaction or avoidance of intimacy

  • Urogenital health. Higher risk of infections or urinary dysfunction

  • Tissue health. Ongoing degeneration of collagen and mucosal integrity

Conventional Treatments and their Limitations:

COâ‚‚ , Er:YAG), radiofrequency , surgical vaginoplasty and injectable fillers (e.g., hyaluronic acid) marketed to improve vaginal tightness, dryness, urinary incontinence, or sexual satisfaction are limited for several reasons:

Lack of durable tissue regeneration

Superficial tissue remodeling or transient inflammation, without restoring the underlying cellular and extracellular matrix

Absence of stem cell activity

They do not promote true biological rejuvenation, as they lack the ability to replace senescent cells or activate regenerative pathways.

Short-lived results

Any improvements is temporary

Limited scientific evidence:

Many claims are based on poorly controlled studies, with inconsistent outcome measures.

These "solutions" fail to deliver the promised regenerative outcomes and result in adverse effects, making them less suitable for long-term restoration of vaginal health.

Risks and Side Effects:

  • Vaginal burns, scarring, pain, or dyspareunia (painful intercourse)

  • Fibrosis or unintended tissue damage

  • Exacerbation of dryness or discomfort in some cases

Can’t wait to feel like yourself again?

How?

It’s easier than you think. Discover the world’s most advanced Stem Cell and Exosomes treatment. Reach out to us — we’re here for you and happy to answer any questions you may have.

Where?

Como (Italy)
Milano (Italy)
Rome (Italy)
Varese (Italy)
Falciano (RSM)

The Power of expanded Mesenchymal Stem Cells (MSCs)

MSCs derived from umbilical cord or adipose tissue, possess regenerative, anti-inflammatory, and immunomodulatory properties.

  • Stimulate fibroblast activity. promoting new collagen and elastin

  • Enhance angiogenesis. restoring healthy blood flow and oxygenation

  • Rebuild extracellular matrix. improving tissue tone and hydration

  • Modulate local inflammation. reducing chronic irritation and tissue degradation

  • Support epithelial regeneration. thickening the mucosal lining and restoring natural lubrication

Clinical Results and Benefits of MSCs-based treatment:

  • Improved vaginal hydration and lubrication

  • Restoration of elasticity and firmness

  • Reduction in pain during intercourse (dyspareunia)

  • Decrease in urinary symptoms and infections

  • Enhanced overall sexual well-being and confidence

  • Increased tone of the vaginal wall

These results are long-lasting and non-hormonal, making stem cell-based vaginal rejuvenation an ideal solution for women who cannot (or prefer not to) use hormone replacement therapies.

Stem Cell Procedure

Let’s clarify with accurate information:

Stem Cells obtained from a fat sample require at least two weeks of processing before they can be used; otherwise, the treatment is ineffective and potentially harmful:

  • Fat that is harvested and manipulated for use in the same session is both useless and harmful.
  • There are no Stem Cells in the blood, so treatments claiming to use stem cells extracted from blood are not scientifically valid. The Stem Cells used to treat hematological diseases are found in the bone marrow, not in the blood.
  • The hematopoietic stem cells found in umbilical cord blood are useful for treating blood disorders, but not for counteracting the aging processes of the human body

The Stem Cell Source

Mesenchymal stem cells are the same regardless of whether they are derived from Adipose Tissue or Umbilical Cord Tissue. The only difference lies in their biological age, which reflects the age of the tissue of origin.

Adipose Tissue Derived Stem Cells 

The treatment requires a fat collection, stem cell extraction, and expansion. The entire process takes approximately 2–3 weeks. Therefore, from the moment of fat harvesting, a waiting period of 2–3 weeks is necessary before the treatment can be performed.

Umbilical Cord Tissue derived Stem Cells

The treatment does not require fat harvesting and can be performed within 2–3 days of the request.

Learn how Stem Cells and Exosomes can change your life!

When?

Today! Reach out to us with confidence and discover the world’s most innovative solutions for Vulvo-Vaginal Rejuvenation. Our experts are here for you — ready to provide all the information and support you need to feel like yourself again.

Where?

Como (Italy)
Milano (Italy)
Rome (Italy)
Varese (Italy)
Falciano (RSM)

Stromal Vascular Fraction (SVF) VS Mesenchymal Stem Cells (MSC)

In the regenerative medicine landscape, many providers offer therapies labeled as "Stem Cell treatments" that utilize Stromal Vascular Fraction (SVF)—a heterogeneous mix of cells extracted from adipose tissue. While SVF contains some Stem Cells, it also includes various other cell types, leading to variability in treatment outcomes.
At our Clinic, we prioritize precision and efficacy by exclusively using Mesenchymal Stem Cells (MSCs). These are meticulously isolated and expanded in controlled laboratory settings, ensuring a pure, potent, and standardized cell population. This approach enhances the therapeutic potential and consistency of our treatments.

Standard Product and Therapy

MSC
YES, A pharma-grade product derived from a cell isolation and culture process, subject to strict quality control procedures

SVF
NO, Composition varies based on the collection site, the patient’s biological age, the digestion technique used, and several other factors.

Cellular Homogeneity

MSC
YES, Isolated and phenotyped cells

SVF
NO, Heterogeneous cell population

Concentration of MSC

MSC
100%

SVF
Between 0,001% and 0,01% of the total cells within

MSC per 10ml FAT

MSC
>100.000.000 after expansion

SVF
Around 9.000

Microphages per 10ml FAT

MSC
0 - Eliminated through isolation of MSCs

SVF
>400.000

Side Effects

MSC
NO

SVF
YES, often unpredictable, usually mediated by inflammatory processes caused by the macrophage population or potential bacterial contamination

Dosage

MSC
VARIOUS DOSAGES AVAILABLE
10-200 millions of MSC (based on indications)

SVF
SINGLE DOSAGE
not tailored to treatment

Safety

MSC
Pharma-grade production process, subjected to quality controls that ensure product sterility and biological safety

SVF
The production process is not monitorable and not subject to quality and biological safety controls

Treatments from 1 fat Collection

MSC
≥10

SVF
1

Phenotyping

MSC
YES

SVF
NO

Cellular Composition

MSC
Mesenchymal Stem Cells

SVF
Pericytes, Macrophages, Endothelial Cells, Mesenchymal Stem Cells, Adipocytes, Lymphocytes, Fibroblasts

Quality Control

MSC
Endotoxins, Mycoplasma, Anaerobic/Aerobic Bacteria, Viruses, Phenotype

SVF
None

Production Time

MSC
2-4 Weeks

SVF
1 hour

FDA Approval

MSC
YES (Ryoncil 18-12-2024)

SVF
NO

EMA Approval

MSC
YES (Alofisel, Spherox, Ryoncil)

SVF
NO

Usage

MSC
Autologous and Allogenic Localized and Systemic

SVF
Strictly Autologous, Homologous, and Localized

    POWERED BY

    BioScience Institute

    As the world’s leading center of Stem Cell and Regenerative Medicine, Bioscience offers unparalleled service and treatments, unique only to it. Bioscience offers the most advanced personalized expanded adipose derived Stem Cell therapies across Europe – including Rome, Milan, and San Marino, and the Middle East, including Dubai.

    The team at Bioscience Institute does not believe in using invasive surgeries when they can be partially replaced by cell biology. Therefore, they have designed an alternative method of extracting stem cells from adipose tissue. As a distinctive and versatile offering, adipose tissue provides an effective solution to all of Bioscience regenerative services, ranging from to hair loss treatments, to skin aging, to body reshaping treatments.

    Bioscience Institute Vision

    The beauty of regenerative medicine therapies and Stem Cell treatments comes from the ability to use your own body to help heal and enhance your well-being through living body tissue. Bioscience Institute’s vision is based on using this most effective and advanced Stem Cell treatments that is based on cell biology and Exosomes to help amplify our natural healing process in the areas it is needed most or take over the function of damaged tissue altogether.

    Stem cells verified treatments

    With the ability to develop methods to regrow, repair, or replace damaged cells and tissues, using Stem Cell & regenerative medicines provides a natural method of treatment that is less traumatic to the body and more effective than other more invasive treatments and surgeries. The stem cell therapies provided by Bioscience Institute are verified in Europe and the Middle East by scientific evidence of increased safety and efficiency than any other treatment method.

    Scientific Research

    The Bioscience’s profits are consistently reinvested into developing research. Avoiding a flashy commercial profile allows us to concentrate on using investments to create better treatments and ultimately help clients globally. Due to this commitment, Bioscience Institute has instigated important scientific collaborations with leading universities, pioneering procedures and methods around cell products.

    Bioscience Cell Factory and Clinic in Dubai, San Marino, Italy & Switzerland

    Bioscience Institute is the first and only GMP-certified Clinic in the Middle East and Europe, offering stem cell treatments with the most advanced personalized autologous cell therapies worldwide.
    Offering a unique service and treatment sets it apart from any form of competition and allows it to give clients the care, attention, and treatment they deserve.

    • Bioscience Clinics in the Middle East and Europe include a fully equipped facility needed to carry out any treatments offered, whether Stem Cell treatments or banking.
    • Bioscience Laboratory is a dedicated Cell Banking Factory used to store and expand Adipose-Derived Cells and Fibroblasts to help ensure that the clients’ needs can always and easily be catered to.